Abstract
The study of Luke 4:18-19 presents a rich foundation for understanding the mission and ministry of Jesus Christ, particularly regarding his proclamation of liberation, healing, and restoration to the marginalized and oppressed.[1] In the context of contemporary mission and pastoral ministry, Ghanaian pastors encounter diverse challenges ranging from socio-economic issues to spiritual warfare, all within a rapidly changing cultural landscape. However, amidst these challenges lie invaluable lessons and principles embedded within Luke 4:18-19, offering timeless wisdom for effective mission and ministry. The study employed both historical and exegetical approaches to explore the implications of the text and its application to the context of Ghanaian pastors. It also discusses the nature of Jesus’ mission and ministry, mission and ministry in the early Church and ministry to the poor among the church Fathers in order to draw informed conclusions for the text’s implications. This study argues that delving into the contextual significance of Luke 4:18-19, by elucidating its implications for Ghanaian pastors, is key to providing valuable insight on biblical exegesis, interpretation, Christian mission and ministry among young, gifted, but desperate pastors in Ghana.